We must find out in the natal chart the inharmonious interactions of the III and XII houses of the horoscope with the VIII house of the horoscope. If we find only the combination III | XII ~ X or III | XII ~ VIII in the horoscope – this can not be an indication of a premature death of a brother or sister, but if we find both parts of the formula – then this is an indication of such loss or premature death of a brother or sisters. So, the second part of the formula is:
2) III | XII ~ VIII.
(III or XII house inharmoniously interacts “~” with the VIII house in the natal chart)

Thus, the whole formula for the loss or premature death of a brother or sister in the horoscope can be written down as:
III | XII ~ X
III | XII ~ VIII
This formula can also be used for nephews and nieces.

But there are brothers and sisters who do not belongs to the third house of the horoscope, but to the 9th house. For them, the corresponding formula will look like the following:
IX | X ~ VIII
IX | X ~ IV
It should be noted that in the natal chart we can observe only indirect indications of events with close people. Direct instructions we can find only in the horoscope of an exact relative.

Example. As an example of work of a formula the natal chart of Cynthia Ann Crawford who lost the brother has been researched.

Let’s find the first part of the formula III | XII ~ X in this horoscope:

1) ♇ r (X) III – Pluto retrograde, ruler of 10th houses is in the 3rd house.
2) ♇ r III ☍ ♂ (X) – Pluto retrograde, an element of the 3rd house, strikes Mars, the ruler of the 10th house.
3) ☿ (III) ☍ ♇ r (X) – Mercury, the ruler of the 3rd house strikes Pluto retrograde, the ruler of the 10th house.
4) ☿ (XII) ☍ ♇ r (X) – Mercury, the ruler of the 12th house strikes Pluto retrograde, the ruler of the 10th house.
5) ☿ (XII) ☌ ♂ (X) – Mercury, the ruler of the 12th house, damages Mars, the ruler of the 10th house.
6) ☿ (III) ☌ ♂ (X) Mercury, the ruler of the 3rd house, damages Mars, the ruler of the 10th house.
On the first part of the formula, we have six indications, with three indications sufficient to carry it out. As we can see the number of indications exceeded twice. The first part of the formula is present.

Now let’s find the second part of the formula (III | XII ~ VIII) in this horoscope

1) ♇ r III ☌ ♅ (VIII) – Pluto is retrograde, the element of the 3rd house, strikes Uranus, the ruler of 8th house.
2) ♇ r III ☍ ♄ (VIII) – Pluto is retrograde, the element of the 3rd house, strikes Saturn, the ruler of 8th house.
3) ♅ III ☍ ♄ VIII – Uranus, the element of the 3rd house, strikes Saturn, the ruler of the 8th house.
4) ♅ (VIII) III – Uranus, the ruler of 8th houses in the 3rd house.
5) ☿ (III) ☍ ♅ (VIII) – Mercury, the ruler of 3rd house strikes Uranus, the ruler of the 8th house.
6) ☿ (XII) ☍ ♅ (VIII) – Mercury, the ruler of the 12th house strikes Uranus, the ruler of the 8th house.
7) ☿ (III) ☌ ♄ (VIII) – Mercury, ruler of the 3rd houses damages Saturn, the ruler of the 8th house.
8) ☿ (XII) ☌ ♄ (VIII) – Mercury, the ruler of the 12th house strikes Saturn, ruler of the 8th house.
9) ☿ (III) ☌ ☽ VIII – Mercury, the ruler of the 3rd house, damages the Moon, the element 8th of the house.
10) ☿ (XII) ☌ ☽ VIII – Mercury, the ruler of the 12th house, damages the Moon, the element of the 8th house.
11) ☽ (XII) VIII – Moon, ruler of the 12th house is in the 8th house.
12) ☽ (XII) ☌ ☉ VIII – Moon, the ruler of the 12th house is in conjunction with the Sun, the element of the 8th house.
13) ☽ (XII) ☌ ⚸ VIII – Moon, ruler of the house 12th in conjunction with Lilith, the element of the 8th house.

The second part of the formula is also fulfilled with an excess of more than 4 times.

«In a preview for her appearance on Oprah’s Master Class on OWN, the 49-year-old supermodel talks about her younger brother, Jeff, who died of leukemia when he was just 3 years old. Crawford was 8 years old when Jeff was first diagnosed. He was only 2 years old at the time.»

The subject of death in astrology is very difficult and unpleasant, but necessary. Knowing that in our horoscope we have indications of premature loss of a brother or sister, we can take timely measures and try to prevent this loss. First and foremost, it is necessary to contact an astrologer in order to find out which of the relatives is in danger (if any), in order to prevent a sad outcome. The ability to prevent a negative event in a number of situations is possible.